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Curr Obes Rep 9 , 391401 (2020)

Tirzepatide may produce slightly greater average results based on current data, but semaglutide has a longer track record and may be more accessible

The glucagon-like peptide 1 receptor agonist exendin-4 improves reference memory performance and decreases immobility in the forced swim test

It is available only through specialized research programs or specific compounding pharmacies under a doctors strict medical supervision

Although opioids are effective pain relievers, they can cause serious side effects such as respiratory depression (deaths from respiratory depression have sparked a widespread "opioid crisis" [1,2] , especially in North America), addiction and constipation, thus limiting their clinical application